Annotation Detail

Information
Associated Genes
EIF4EBP1
Associated Variants
EIF4EBP1 MUTATION
EIF4EBP1 MUTATION
Associated Disease
Helicobacter pylori infection
Source Database
DisGeNET
Description
Inhibition of PI3K and Akt kinase prevented the phosphorylation of 4E-BP1, suggesting that PI3K signalling is involved in the regulation of translation initiation during H. pylori infection.
Pubmed
25194338
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs