Annotation Detail

Information
Associated Genes
EPHX2
Associated Variants
EPHX2 p.Lys55Arg (p.K55R) ( ENST00000380476.7, ENST00000517536.5, ENST00000518379.5, ENST00000521400.6, ENST00000521780.5 )
EPHX2 p.Lys55Arg (p.K55R) ( ENST00000380476.7, ENST00000517536.5, ENST00000518379.5, ENST00000521400.6, ENST00000521780.5 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
The functional K55R polymorphism of the EPHX2 gene confers a higher risk of hypertension prevalence and increases the risk of incident ischemic stroke in male homozygotes.
Pubmed
20065888
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0829957921145475
Year of publication
2010
Drugs