Annotation Detail

Information
Associated Genes
NOS3
Associated Variants
NOS3 c.-51-735C>T ( ENST00000297494.8, ENST00000461406.5 )
NOS3 c.-51-735C>T ( ENST00000297494.8, ENST00000461406.5 )
Associated Disease
Aneurysm
Source Database
DisGeNET
Description
Although not predictive of SAH in the population at large, our data suggest that among persons with known intracranial aneurysms, eNOS T-786C genotype may be a factor influencing the size at which an aneurysm ruptures, a finding that should be taken into consideration along with other anatomic features of the aneurysm.
Pubmed
14576373
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00481000882732476
Year of publication
2003
Drugs