Annotation Detail

Information
Associated Genes
NOS3
Associated Variants
NOS3 c.-51-735C>T ( ENST00000297494.8, ENST00000461406.5 )
NOS3 c.-51-735C>T ( ENST00000297494.8, ENST00000461406.5 )
Associated Disease
coronary artery vasospasm
Source Database
DisGeNET
Description
Because the endothelial nitric oxide synthase (eNOS) T-786C polymorphism is associated with reduced nitric oxide production and coronary artery spasm in Japanese patients, we speculated that it might be reversibly associated with Prinzmetal's variant angina in white Americans.
Pubmed
20211321
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.138435641214722
Year of publication
2010
Drugs