Annotation Detail

Information
Associated Genes
SCN5A
Associated Variants
SCN5A p.Arg1193Gln (p.R1193Q) ( ENST00000413689.6, ENST00000333535.9, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
SCN5A p.Arg1193Gln (p.R1193Q) ( ENST00000333535.9, ENST00000413689.6, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
Associated Disease
Sudden unexpected nocturnal death syndrome
Source Database
DisGeNET
Description
DNA analysis revealed a missense mutation (R1193Q) in the SCN5A gene, previously linked with familial sudden unexpected nocturnal death syndrome, also known as Brugada syndrome.
Pubmed
15851440
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2005
Drugs