Annotation Detail
Information
- Associated Genes
- ALOX5AP
- Associated Variants
-
ALOX5AP c.117-3417G>A
(
ENST00000617770.4 )
ALOX5AP c.241+767G>A ( ENST00000617770.4, ENST00000380490.5 )
ALOX5AP c.494+2385A>C ( ENST00000617770.4, ENST00000380490.5 )
ALOX5AP c.495-2036A>G ( ENST00000380490.5, ENST00000617770.4 )
ALOX5AP c.117-3417G>A ( ENST00000617770.4 )
ALOX5AP c.241+767G>A ( ENST00000380490.5, ENST00000617770.4 )
ALOX5AP c.494+2385A>C ( ENST00000380490.5, ENST00000617770.4 )
ALOX5AP c.495-2036A>G ( ENST00000380490.5, ENST00000617770.4 ) - Associated Disease
- Ischemic Cerebrovascular Accident
- Source Database
- DisGeNET
- Description
- These results suggest the ALOX5AP SNP A allele in rs4073259 and genotype rs9579646 GG, rs9551963 AC, and haplotype rs9315050 & rs9551963 AAAC were associated with an increased risk of ischemic stroke in the Han population, while rs4073259 GG was associated with a decreased risk.
- Pubmed
- 22849376
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00407162808120455
- Year of publication
- 2012
Drugs