Annotation Detail

Information
Associated Genes
SMPD1
Associated Variants
SMPD1 p.Arg542Ter (p.R542*) ( ENST00000527275.5, ENST00000342245.9 )
SMPD1 p.Arg542Ter (p.R542*) ( ENST00000342245.9, ENST00000527275.5 )
Associated Disease
Niemann-Pick Diseases
Source Database
DisGeNET
Description
We present a case of a 9-month infant with clinical manifestations intermediate between types A and B NPD and genetically illustrating a novel R542X mutation in the exon 6 of SMPD1.
Pubmed
23188845
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.266098145806366
Year of publication
2014
Drugs