Annotation Detail

Information
Associated Genes
SMPD1
Associated Variants
SMPD1 p.Arg542Ter (p.R542*) ( ENST00000527275.5, ENST00000342245.9 )
SMPD1 p.Arg542Ter (p.R542*) ( ENST00000342245.9, ENST00000527275.5 )
Associated Disease
Niemann-Pick disease, type B
Source Database
DisGeNET
Description
R542X mutation in SMPD1 gene: genetically novel mutation with phenotypic features intermediate between type A and type B Niemann-Pick disease.
Pubmed
23188845
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.56516732709119
Year of publication
2014
Drugs