Annotation Detail

Information
Associated Genes
TPM3
Associated Variants
TPM1 p.Met8Arg (p.M8R) ( ENST00000560970.6, ENST00000714017.1, ENST00000267996.11, ENST00000559556.5, ENST00000358278.7, ENST00000561266.6, ENST00000403994.9, ENST00000288398.10, ENST00000610733.1, ENST00000357980.9, ENST00000714014.1, ENST00000559397.6, ENST00000714013.1 )
TPM3 p.Met9Arg (p.M9R) ( ENST00000651641.1, ENST00000368530.7, ENST00000271850.11 )
TPM1 p.Met8Arg (p.M8R) ( ENST00000267996.11, ENST00000288398.10, ENST00000357980.9, ENST00000358278.7, ENST00000403994.9, ENST00000559397.6, ENST00000559556.5, ENST00000560970.6, ENST00000561266.6, ENST00000610733.1, ENST00000714013.1, ENST00000714014.1, ENST00000714017.1 )
TPM3 p.Met9Arg (p.M9R) ( ENST00000271850.11, ENST00000368530.7, ENST00000651641.1 )
Associated Disease
Nemaline Myopathy, Autosomal Dominant
Source Database
DisGeNET
Description
We have previously reported a Met9Arg mutation in the human skeletal muscle alpha tropomyosin gene (TPM3) associated with autosomal dominant nemaline myopathy [Nat.
Pubmed
12163017
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2002
Drugs