Annotation Detail

Information
Associated Genes
F3
Associated Variants
F3 MUTATION
F3 MUTATION
Associated Disease
Dissecting aneurysm of the thoracic aorta
Source Database
DisGeNET
Description
Importantly, administration of valsartan (20 mg/kg, i.p) for 8 weeks significantly reduced plasma TF activity, expression of Egr-1, TLR-2, -4 and TF in thoracic aorta and improved glucose tolerance of streptozotocin-induced diabetic mice.
Pubmed
25109475
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs