Annotation Detail
Information
- Associated Genes
- LIG1
- Associated Variants
-
LIG1 MUTATION
LIG1 MUTATION - Associated Disease
- Central neuroblastoma
- Source Database
- DisGeNET
- Description
- Inhibition of Lig3 and Lig1 led to DSB accumulation and cell death, linking alt-NHEJ to cell survival in neuroblastoma.
- Pubmed
- 25563294
- Section of the abstract supporting the evidence
- UNLABELLED
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs