Annotation Detail

Information
Associated Genes
PTPN11
Associated Variants
PTPN11 p.Gln510Pro (p.Q510P) ( ENST00000687906.1, ENST00000351677.7, ENST00000688597.1, ENST00000690210.1, ENST00000635625.1, ENST00000639857.2 )
PTPN11 p.Gln510Pro (p.Q510P) ( ENST00000351677.7, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
PTPN11 p.Gln510Pro (p.Q510P) ( ENST00000635625.1, ENST00000688597.1, ENST00000351677.7, ENST00000687906.1, ENST00000690210.1, ENST00000639857.2 )
PTPN11 p.Gln510Pro (p.Q510P) ( ENST00000351677.7, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
Associated Disease
Noonan syndrome
Source Database
DisGeNET
Description
We report on a 26-year-old female with features of Noonan syndrome-Multiple Lentigines and a heterozygous mutation: c.1517A > C-p.Gln506Pro in the PTPN11 gene.
Pubmed
22528600
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.694446819376149
Year of publication
2012
Drugs