Annotation Detail

Information
Associated Genes
PTPN11
Associated Variants
PTPN11 p.Asn58His (p.N58H) ( ENST00000687906.1, ENST00000351677.7, ENST00000688597.1, ENST00000392597.5, ENST00000690210.1, ENST00000639857.2, ENST00000635625.1 )
PTPN11 p.Asn58Asp (p.N58D) ( ENST00000351677.7, ENST00000392597.5, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
PTPN11 p.Asn58Tyr (p.N58Y) ( ENST00000351677.7, ENST00000687906.1, ENST00000690210.1, ENST00000639857.2, ENST00000635625.1, ENST00000688597.1, ENST00000392597.5 )
PTPN11 p.Asn58His (p.N58H) ( ENST00000351677.7, ENST00000392597.5, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
PTPN11 p.Asn58Asp (p.N58D) ( ENST00000351677.7, ENST00000392597.5, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
PTPN11 p.Asn58Tyr (p.N58Y) ( ENST00000351677.7, ENST00000392597.5, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
Associated Disease
Noonan syndrome
Source Database
DisGeNET
Description
Does the rare A172G mutation of PTPN11 gene convey a mild Noonan syndrome phenotype?
Pubmed
16804314
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.694446819376149
Year of publication
2006
Drugs