Annotation Detail

Information
Associated Genes
BRAF
Associated Variants
BRAF p.Leu245Phe (p.L245F) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Leu245Phe (p.L245F) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Leu245Phe (p.L245F) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Leu245Phe (p.L245F) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
Associated Disease
Cardio-facio-cutaneous syndrome
Source Database
DisGeNET
Description
We speculate that the impact of p.L245F on BRAF protein function differs either qualitatively or quantitatively from those mutations associated with CFCS.
Pubmed
19416762
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.567057488674088
Year of publication
2009
Drugs