Annotation Detail
Information
- Associated Genes
- IL10RB
- Associated Variants
-
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E)
(
ENST00000290200.7,
ENST00000609556.3,
ENST00000637650.2,
ENST00000433395.7 )
ENSG00000285404 c.1786+50692T>G, DEPDC5 c.3331-673T>G ( ENST00000382111.6, ENST00000382112.8, ENST00000400248.7, ENST00000400249.7, ENST00000433147.2, ENST00000535622.6, ENST00000642696.1, ENST00000644331.1, ENST00000645407.1, ENST00000645560.1, ENST00000645711.1, ENST00000646465.1, ENST00000646969.1, ENST00000651528.2 )
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 )
ENSG00000285404 c.1786+50692T>G, DEPDC5 c.3331-673T>G ( ENST00000382111.6, ENST00000382112.8, ENST00000400248.7, ENST00000400249.7, ENST00000433147.2, ENST00000535622.6, ENST00000642696.1, ENST00000644331.1, ENST00000645407.1, ENST00000645560.1, ENST00000645711.1, ENST00000646465.1, ENST00000646969.1, ENST00000651528.2 ) - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively.
- Pubmed
- 25032264
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2015
Drugs