Annotation Detail

Information
Associated Genes
FCGR3A
Associated Variants
FCGR3A p.Phe176Val (p.F176V) ( ENST00000367967.8, ENST00000436743.7, ENST00000699395.1, ENST00000699397.1, ENST00000699399.1, ENST00000699401.1, ENST00000699396.1, ENST00000426740.8, ENST00000699400.1, ENST00000443193.6, ENST00000699398.1 )
FCGR3A p.Phe176Leu (p.F176L) ( ENST00000443193.6, ENST00000699398.1, ENST00000699401.1, ENST00000699396.1, ENST00000699400.1, ENST00000426740.8, ENST00000699399.1, ENST00000699397.1, ENST00000699395.1, ENST00000436743.7, ENST00000367967.8 )
FCGR3A p.Phe176Val (p.F176V) ( ENST00000367967.8, ENST00000426740.8, ENST00000436743.7, ENST00000443193.6, ENST00000699395.1, ENST00000699396.1, ENST00000699397.1, ENST00000699398.1, ENST00000699399.1, ENST00000699400.1, ENST00000699401.1 )
FCGR3A p.Phe176Leu (p.F176L) ( ENST00000367967.8, ENST00000426740.8, ENST00000436743.7, ENST00000443193.6, ENST00000699395.1, ENST00000699396.1, ENST00000699397.1, ENST00000699398.1, ENST00000699399.1, ENST00000699400.1, ENST00000699401.1 )
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
These results suggest that FCGR3A-158F/V (rs396991) gene polymorphism play a role in the response to rituximab in autoimmune diseases.
Pubmed
23075294
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00325730246496364
Year of publication
2012
Drugs