Annotation Detail
Information
- Associated Genes
- GSTA1
- Associated Variants
-
CYBA p.Tyr72His (p.Y72H)
(
ENST00000696162.1,
ENST00000696157.1,
ENST00000696161.1,
ENST00000696156.1,
ENST00000261623.8,
ENST00000696158.1,
ENST00000569359.5,
ENST00000696163.1,
ENST00000696159.1,
ENST00000567174.5,
ENST00000696160.1 )
rs3957357
CYBA p.Tyr72His (p.Y72H) ( ENST00000261623.8, ENST00000567174.5, ENST00000569359.5, ENST00000696156.1, ENST00000696157.1, ENST00000696158.1, ENST00000696159.1, ENST00000696160.1, ENST00000696161.1, ENST00000696162.1, ENST00000696163.1 )
rs3957357 - Associated Disease
- diffuse large B-cell lymphoma
- Source Database
- DisGeNET
- Description
- Overall, host SNPs affecting doxorubicin pharmacodynamics (CYBA rs4673) and alkylator detoxification (GSTA1 rs3957357) may predict outcome in R-CHOP21-treated DLBCL.
- Pubmed
- 19448608
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs