Annotation Detail
Information
- Associated Genes
- PIK3CG
- Associated Variants
-
PIK3CG MUTATION
PIK3CG MUTATION - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- Phosphatidylinositol 3-kinase (PI3K) pathway deregulation (that is PIK3CA mutations and/or phosphatase and tensin homolog (PTEN) loss) has been shown to enhance breast cancer cell survival and confer resistance to chemotherapeutic agents.
- Pubmed
- 25056500
- Section of the abstract supporting the evidence
- INTRODUCTION
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0439735832770091
Drugs