Annotation Detail
Information
- Associated Genes
- MDM2
- Associated Variants
-
MDM2 MUTATION
MDM2 MUTATION - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- To date, most MDM2 inhibitors have been designed to block the MDM2-p53-binding interphase, and have low or no efficacy against advanced breast cancer with mutant or deficient p53.
- Pubmed
- 25271708
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0209010241501834
Drugs