Annotation Detail

Information
Associated Genes
JAK2
Associated Variants
JAK2 MUTATION
JAK2 MUTATION
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
Associated Disease
leukemia
Source Database
DisGeNET
Description
JAK2 (V617F)-positive ET may evolve in few instances into JAK2-negative leukemia.
Pubmed
19691103
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.144970109187978
Year of publication
2009
Drugs