Annotation Detail
Information
- Associated Genes
- UGT2B15
- Associated Variants
-
UGT2B15 MUTATION
UGT2B15 MUTATION - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- As 4-OHTAM is a UGT2B15 substrate, the upregulation of UGT2B15 by 4-OHTAM in target breast cancer cells is likely to enhance local metabolism and inactivation of 4-OHTAM within the tumor.
- Pubmed
- 25795461
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
Drugs