Annotation Detail

Information
Associated Genes
EPOR
Associated Variants
EPOR MUTATION
EPOR MUTATION
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
Associated Disease
polycythemia vera
Source Database
DisGeNET
Description
HLA-G turns off erythropoietin receptor signaling through JAK2 and JAK2 V617F dephosphorylation: clinical relevance in polycythemia vera.
Pubmed
18059484
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00481000882732476
Year of publication
2008
Drugs