Annotation Detail

Information
Associated Genes
PARP1
Associated Variants
PARP1 MUTATION
PARP1 MUTATION
Associated Disease
breast carcinoma
Source Database
DisGeNET
Description
Poly(ADP-ribose) polymerase inhibitors (PARP inhibitors) represent an important group of promising drugs in managing patients with breast cancer susceptibility gene (BRCA)-1- or BRCA-2-associated BC.
Pubmed
25796377
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
21
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0230725591268258
Drugs