Annotation Detail
Information
- Associated Genes
- EPHB2
- Associated Variants
-
EPHB2 MUTATION
EPHB2 MUTATION - Associated Disease
- Refractory cancer
- Source Database
- DisGeNET
- Description
- By far, the most common clinical resistance mechanism involves reactivation of the MAPK (RAF/MEK/ERK) pathway by a variety of mechanisms.
- Pubmed
- 25320010
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs