Annotation Detail
Information
- Associated Genes
- ABL1
- Associated Variants
-
ABL1 MUTATION
ABL1 MUTATION - Associated Disease
- Refractory cancer
- Source Database
- DisGeNET
- Description
- Point mutations in the ABL1 kinase domain weaken inhibitor binding and represent the most common clinical resistance mechanism.
- Pubmed
- 25686603
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00434306995328485
Drugs