Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL MUTATION
MPL MUTATION
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
Associated Disease
Primary myelofibrosis
Source Database
DisGeNET
Description
Frequency and allele burden of CALR mutations in Chinese with essential thrombocythemia and primary myelofibrosis without JAK2(V617F) or MPL mutations.
Pubmed
25746303
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0514070483465319
Year of publication
2015
Drugs