Annotation Detail

Information
Associated Genes
PARP1
Associated Variants
PARP1 MUTATION
PARP1 MUTATION
Associated Disease
Epithelial ovarian cancer
Source Database
DisGeNET
Description
Women with histologically proven EOC who were randomised to treatment groups in trials that either compared PARP inhibitors with no treatment, or PARP inhibitors versus conventional chemotherapy, or PARP inhibitors together with conventional chemotherapy versus conventional chemotherapy alone.
Pubmed
25991068
Section of the abstract supporting the evidence
SELECTION CRITERIA
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00508145069940506
Drugs