Annotation Detail
Information
- Associated Genes
- MSH3
- Associated Variants
-
MSH3 MUTATION
MSH3 MUTATION - Associated Disease
- Epithelial ovarian cancer
- Source Database
- DisGeNET
- Description
- Together, these results suggest that emodin could act as an adjunct to enhance the anticancer effect of cDDP likely through ROS-related downregulation of MRP1 expression, and may be of therapeutic potential in cDDP-refractory ovarian carcinomas.
- Pubmed
- 25580427
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00318135759484294
Drugs