Annotation Detail
Information
- Associated Genes
- MMP3
- Associated Variants
-
MMP3 MUTATION
MMP3 MUTATION - Associated Disease
- prostate carcinoma
- Source Database
- DisGeNET
- Description
- In conclusion, the present study suggests that AQP3 induces ERK1/2 activation, thereby increasing MMP‑3 expression and secretion, which in turn promotes prostate cancer cell motility and invasion.
- Pubmed
- 25515250
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs