Annotation Detail

Information
Associated Genes
ABL1
Associated Variants
ABL1 MUTATION
ABL1 MUTATION
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
Associated Disease
Myeloproliferative disease
Source Database
DisGeNET
Description
An association between an activating JAK2 mutation (JAK2(V617F)) and BCR/ABL-negative myeloproliferative disorders was recently reported in multiple simultaneous publications.
Pubmed
16225651
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0173722798131394
Year of publication
2005
Drugs