Annotation Detail

Information
Associated Genes
JAK2
Associated Variants
JAK2 MUTATION
JAK2 MUTATION
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
Associated Disease
myelofibrosis
Source Database
DisGeNET
Description
The frequency of the JAK2 V617F was 73% (85% in PV, 65% in ET, and 65% in CIMF).
Pubmed
17255768
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.229044280312592
Year of publication
2007
Drugs