Annotation Detail

Information
Associated Genes
CFH
Associated Variants
CFH MUTATION
CFH MUTATION
Associated Disease
age related macular degeneration
Source Database
DisGeNET
Description
Common polymorphisms in complement alternative pathway (AP) proteins C3 (C3(R102G)), factor B (fB(R32Q)), and factor H (fH(V62I)) are associated with age-related macular degeneration (AMD) and other pathologies.
Pubmed
21555552
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.48
Year of publication
2011
Drugs