Annotation Detail

Information
Associated Genes
CTLA4
Associated Variants
CTLA4 MUTATION
CTLA4 MUTATION
rs733618 ( ENST00000696479.1 )
rs733618 ( ENST00000696479.1 )
Associated Disease
Periodontitis, Juvenile
Source Database
DisGeNET
Description
In addition, comparison of CTLA-4 SNPs between patients with CP and aggressive periodontitis (AgP) revealed that heterozygosity in -1722 T/C polymorphism of CTLA-4 gene had a significantly higher risk for CP compared with AgP with a calculated odds ratio of 2.18 (95% CI; 1.17-4.06, P=0.01).
Pubmed
22497911
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2012
Drugs