Annotation Detail

Information
Associated Genes
MMP12
Associated Variants
MMP12 MUTATION
MMP12 MUTATION
MMP12 p.Gln356= (p.Q356=) ( ENST00000571244.3 )
MMP12 p.Gln356His (p.Q356H) ( ENST00000571244.3 )
MMP12 p.Asn357Ser (p.N357S) ( ENST00000571244.3 )
MMP12 p.Asn357Thr (p.N357T) ( ENST00000571244.3 )
Associated Disease
Chronic Obstructive Airway Disease
Source Database
DisGeNET
Description
To investigate the association of 3 polymorphisms of MMP genes (MMP-1 -1607G-->GG, MMP-9 -1562C-->T and MMP-12 N357S), which have been reported to be associated with COPD-related phenotypes, with the risk of COPD in a Korean population.
Pubmed
20160424
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0247323430559516
Year of publication
2010
Drugs