Annotation Detail
Information
- Associated Genes
- HTR2A
- Associated Variants
-
HTR2A MUTATION
HTR2A MUTATION
HTR2A p.Ser34= (p.S34=) ( ENST00000542664.4, ENST00000543956.5 )
HTR2A p.Ser34= (p.S34=) ( ENST00000542664.4, ENST00000543956.5 ) - Associated Disease
- obsessive-compulsive disorder
- Source Database
- DisGeNET
- Description
- Both genotypic and allelic distributions of the 5-HT receptor 2A (5-HT2A) T102C variant were found to be significantly different between the TTM and control subjects (p=0.028 and p=0.024, respectively), and a trend towards significance was noted between the TTM and OCD subjects (p=0.084 and p=0.080 for genotype and allele analyses, respectively), with the T102T-genotype found to confer susceptibility to the development of TTM.
- Pubmed
- 16910371
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.140726728323204
- Year of publication
- 2006
Drugs