Annotation Detail

Information
Associated Genes
HTR1B
Associated Variants
HTR1B MUTATION
HTR1B MUTATION
DRD2 p.His313= (p.H313=) ( ENST00000544518.5, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000346454.7 )
HTR1B p.Val287= (p.V287=) ( ENST00000369947.5 )
DRD2 p.His313= (p.H313=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
HTR1B p.Val287= (p.V287=) ( ENST00000369947.5 )
Associated Disease
Headache
Source Database
DisGeNET
Description
Gene polymorphisms including serotonin (5-HT)(1B) receptor G861C and dopamine receptor 2 (DRD2) C939T, personality traits and characteristics of headache were investigated in 46 consistent responders and 14 inconsistent responders to triptans.
Pubmed
21822697
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Year of publication
2012
Drugs