Annotation Detail

Information
Associated Genes
DRD2
Associated Variants
DRD2 MUTATION
DRD2 MUTATION
DRD2 p.His313= (p.H313=) ( ENST00000544518.5, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000346454.7 )
DRD2 p.His313= (p.H313=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
Associated Disease
Migraine Disorders
Source Database
DisGeNET
Description
The multivariate stepwise logistic regression analysis revealed that age, periorbital/deep orbital pain and C/C genotype carrier at DRD2 C939T were significant factors that contributed independently to the negative response to triptans in patients with migraine.
Pubmed
21822697
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0150924623579738
Year of publication
2012
Drugs