Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
Mood Disorders
Source Database
DisGeNET
Description
A polymorphism of the human Brain Derived Neurotrophic Factor (BDNF) gene that produces a valine-to-methionine substitution at codon 66 (Val66Met) is linked to adult anxiety and mood disorders, possibly through effects on brain circuitry function.
Pubmed
19931400
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0272836023831975
Year of publication
2010
Drugs