Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
brain ischemia
Source Database
DisGeNET
Description
Even though previous brain ischemia and WM lesion studies have been conducted and indicated that brain-derived neurotrophic factor (BDNF) might protect against neuronal cell death, the interaction between regional WMH volume and the BDNF Val66Met polymorphism on the cognitive performance of healthy elderly population remains unclear.
Pubmed
24275008
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.120542883744161
Year of publication
2013
Drugs