Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
Depressive Symptoms
Source Database
DisGeNET
Description
The serotonin transporter polymorphism (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF) val66met polymorphism have both been linked to depression symptoms and to depression diagnosis (MDD) in interaction with adversity; there have also been failures to find the effects.
Pubmed
21420735
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00678604680200758
Year of publication
2011
Drugs