Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
Mental Depression
Source Database
DisGeNET
Description
A brain-derived neurotrophic factor (BDNF) prodomain single-nucleotide polymorphism resulting in a valine to methionine substitution (Val66Met) has been associated with depression-related phenotypes and brain alterations involving regions consistently associated with major depressive disorder (MDD).
Pubmed
23165919
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.119718606592274
Year of publication
2013
Drugs