Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
Impaired cognition
Source Database
DisGeNET
Description
Our findings supported the hypothesis that the BDNF Val66Met polymorphism may affect susceptibility to regional WMH volume and such genotype-by-WMH interaction effect is correlated with cognitive decline in non-demented elderly males, in which the Met allele plays a protective role.
Pubmed
24275008
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0078718142903288
Year of publication
2013
Drugs