Annotation Detail

Information
Associated Genes
MLH1
Associated Variants
MLH1 MUTATION
MLH1 MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
As one of the most essential components of mismatch repair system, MutL homolog 1 (MLH1) plays an increasingly implicated role in initiation and promotion of colorectal carcinogenesis, with germ-line mutations in different loci.
Pubmed
25986311
Section of the abstract supporting the evidence
PURPOSE
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0249726522313879
Drugs