Annotation Detail

Information
Associated Genes
RNASEL
Associated Variants
RNASEL MUTATION
RNASEL MUTATION
RNASEL p.Arg462Gln (p.R462Q) ( ENST00000539397.1, ENST00000367559.7 )
RNASEL p.Arg462Gln (p.R462Q) ( ENST00000367559.7, ENST00000539397.1 )
Associated Disease
prostate carcinoma
Source Database
DisGeNET
Description
Xenotropic murine leukemia virus (MLV)-related virus (XMRV) was initially identified in prostate cancer (PCa) tissue, particularly in the prostatic stromal fibroblasts, of patients homozygous for the RNASEL R462Q mutation.
Pubmed
21447170
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0143864192202561
Year of publication
2011
Drugs