Annotation Detail

Information
Associated Genes
HLA-DRB1
Associated Variants
HLA-DRB1 MUTATION
HLA-DRB1 MUTATION
Associated Disease
primary sclerosing cholangitis
Source Database
DisGeNET
Description
These patients had a significantly lower frequency of the strongest PSC risk factor, HLA-B*08, than patients without increased IgG4, and significantly higher frequencies of HLA-B*07 and HLA-DRB1*15.
Pubmed
25655558
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00407162808120455
Drugs