Annotation Detail

Information
Associated Genes
HLA-DRB1
Associated Variants
HLA-DRB1 MUTATION
HLA-DRB1 MUTATION
Associated Disease
primary sclerosing cholangitis
Source Database
DisGeNET
Description
Our study shows that classical HLA class I and II alleles, predominantly at HLA-B and HLA-DRB1, are the main risk factors for PSC in the MHC.
Pubmed
25521205
Section of the abstract supporting the evidence
CONCLUSIONS/SIGNIFICANCE
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00407162808120455
Drugs