Annotation Detail

Information
Associated Genes
RNASEL
Associated Variants
RNASEL MUTATION
RNASEL MUTATION
RNASEL p.Asp541Glu (p.D541E) ( ENST00000367559.7, ENST00000539397.1 )
RNASEL p.Arg462Gln (p.R462Q) ( ENST00000539397.1, ENST00000367559.7 )
RNASEL p.Asp541Glu (p.D541E) ( ENST00000367559.7, ENST00000539397.1 )
RNASEL p.Arg462Gln (p.R462Q) ( ENST00000367559.7, ENST00000539397.1 )
Associated Disease
Prostate cancer, familial
Source Database
DisGeNET
Description
Genotyping of HPC2/ELAC2 variants (S217L, A541T), along with RNASEL variants (R462Q and E541D) was completed in 155 African American sporadic and 88 familial prostate cancer cases, and 296 healthy male controls.
Pubmed
18767027
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.364343069953285
Year of publication
2008
Drugs