Annotation Detail

Information
Associated Genes
RNASEL
Associated Variants
RNASEL MUTATION
RNASEL MUTATION
RNASEL p.Arg462Gln (p.R462Q) ( ENST00000539397.1, ENST00000367559.7 )
RNASEL p.Arg462Gln (p.R462Q) ( ENST00000367559.7, ENST00000539397.1 )
Associated Disease
Prostate cancer, familial
Source Database
DisGeNET
Description
The RNASEL (encoding ribonuclease L) gene Glu265X mutation has been implicated in familial prostate cancer, and an association between the RNASEL Arg462Gln variant and sporadic and familial prostate cancer, has also been suggested.
Pubmed
15981205
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.364343069953285
Year of publication
2005
Drugs