Annotation Detail

Information
Associated Genes
POLD1
Associated Variants
POLD1 MUTATION
POLD1 MUTATION
Associated Disease
Malignant glioma
Source Database
DisGeNET
Description
These results indicate that the ability to suppress the malignant phenotype by down-regulating CDC2 expression may provide a new gene therapy approach for overcoming CDC2-associated chemoresistance in patients with malignant glioma.
Pubmed
25433945
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs