Annotation Detail

Information
Associated Genes
DDIT3
Associated Variants
IL19 c.-149+1984T>G ( ENST00000659642.2, ENST00000659997.3, ENST00000656872.2, ENST00000659065.2, ENST00000664374.2 )
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
rs1800890 ( ENST00000659997.3, ENST00000656872.2 )
rs10494879 ( ENST00000659997.3, ENST00000656872.2 )
rs6676671 ( ENST00000659997.3, ENST00000656872.2 )
IL19 c.-149+1984T>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
rs1800890 ( ENST00000656872.2, ENST00000659997.3 )
rs10494879 ( ENST00000656872.2, ENST00000659997.3 )
rs6676671 ( ENST00000656872.2, ENST00000659997.3 )
Associated Disease
lymphoma
Source Database
DisGeNET
Description
Five hundred patients with aggressive NHL treated with CHOP/CHOEP were analyzed for IL-10 gene polymorphisms, including distal loci -7400InDel, -6752AT (rs6676671), and -6208CG (rs10494879) in comparison with proximal loci -3538AT (rs1800890), -1087AG (rs1800896), and -597AC (rs1800872) according to the incidence and outcome of the lymphoma.
Pubmed
18559596
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00434306995328485
Year of publication
2008
Drugs